Cannabidiol (CBD) is one of the major constituents of Cannabis sativa L. That lacks psychotomimetic and rewarding properties and inhibits the rewarding and reinforcing effects of addictive drugs such as cocaine, methamphetamine (METH), and morphine. Additionally, CBD’s safety profile and therapeutic potential are currently evaluated in several medical conditions, including pain, depression, movement disorders, epilepsy, multiple sclerosis, Alzheimer’s disease, ischemia, and substance use disorder.
Adverse Effects of THC- or CBD-Containing Products
The goal of this systematic review is to summarize the available preclinical and clinical data on the impact of CBD on addictive behaviors. MEDLINE and PubMed were searched for English and French language articles published before 2015. In all, 14 studies were found, 9 of which were conducted on animals and the remaining 5 on humans. A limited number of preclinical studies suggest that CBD may have therapeutic properties on opioid, cocaine, and psychostimulant addiction, and some preliminary data suggest that it may be beneficial in cannabis and tobacco addiction in humans. Further studies are clearly necessary to fully evaluate the potential of CBD as an intervention for addictive disorders.
Are there any bad effects from stopping CBD suddenly?
CBD has also exhibited therapeutic potential for treating alcohol use disorder. CBD’s effects on ethanol reinforcement, motivation, and relapse in mice were shown in a recent study. Ethanol use, SA, CPP, and ethanol-induced relapse were all reduced upon CBD administration (Viudez-Martínez et al., 2018). In another study, rats were trained to self-administer alcohol at 24h intervals for seven days and then treated with CBD. CBD diminished the stress-induced drug-seeking behavior and alcohol’s sedative effects and inhibited the motivation for alcohol SA.
Long-Term Effects of Cannabis on the Brain: Neuroimaging Studies
Advocates say medicinal cannabis offers effective relief when other treatments are failing. But Australian guidelines say there’s limited evidence to support its use. That said, preliminary research is cannabidiol addictive on CBD and its benefits are promising in relation to helping with mild to moderate health concerns and it is generally considered a safe substance.
CBD as a Potential Treatment for Addiction
Those can include dangerous heavy metals and significant doses of THC (tetrahydrocannabinol) — the compound in marijuana that induces a high. No animal study was found on hallucinogen-, sedative-, tobacco-, or alcohol-addictive behaviors. More research is needed to truly understand the potential benefits of using CBD as a complementary treatment for emotional and physical health conditions. Cannabis-derived CBD products may be more effective than those from hemp, but industrial hemp-derived CBD still provides many health benefits.
- Withdrawal from CBD does not lead to the same symptoms as other addictive substances, and ongoing research is shedding more light on this topic.
- If you’re pregnant, you shouldn’t use medical marijuana unless your doctor says it’s OK.
- Marijuana refers to dried leaves, flowers, stems, and seeds from the hemp plant, Cannabis sativa.
- This study aims to better understand healthy development and shed light on how early exposure to cannabis and other substances, stressors, and trauma affect brain development and mental health, and how to reduce adverse outcomes.
- CBD is well-tolerated by humans, even in doses reaching 1,500 mg daily.
Studies showed it was effective in comparison to a placebo in reducing the frequency of seizures. In 2018, the first FDA-approved drug, cannabidiol (Epidiolex), containing CBD was released on the market to treat two different kinds of epilepsy — Dravet syndrome and Lennox-Gastaut syndrome. The emergency and referral resources listed above are available to individuals located in the United States and are not operated by the National Institute on Drug Abuse (NIDA).
Who Gets CUD?
Dr. Matharu-Daley says it’s important to talk to your doctor about whether CBD could affect your existing prescriptions. According to federal law, all hemp-derived CBD products must contain less than 0.3% THC. You should always check your state’s laws https://ecosoberhouse.com/ before purchasing CBD or CBD-derived products.
